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CAS Registry Number: 1622-61-3

CAS Name: 5-(2-Chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one
Additional Names: 7-nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one
Manufacturers' Codes: Ro-5-4023
Trademarks: Clonopin (Roche); Iktorivil (Roche); Klonopin (Roche); Landsen (Sumitomo); Rivotril (Roche)
Molecular Formula: C15H10ClN3O3
Molecular Weight: 315.71
Percent Composition: C 57.07%, H 3.19%, Cl 11.23%, N 13.31%, O 15.20%
Properties: White crystals from ethanol-methylene chloride, mp 236.5-238.5°. uv max (7.5% methanol in isopropanol): 248, 310 nm (e 14500, 11600). Soly in mg/ml at 25°: acetone 31; chloroform 15; methanol 8.6; ether 0.7; benzene 0.5; water <0.1. pK1 1.5, pK2 10.5. LD50 orally in mice: >4000 mg/kg (Blum).
Melting point: mp 236.5-238.5°
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