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CAS Registry Number: 59467-70-8
CAS Name: 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
Molecular Formula: C18H13ClFN3
Molecular Weight: 325.77
Percent Composition: C 66.36%, H 4.02%, Cl 10.88%, F 5.83%, N 12.90%
Properties: Colorless crystals from ether/methylene chloride/hexane, mp 158-160°. uv max (2-propanol): 220 nm (e 30000).
Melting point: mp 158-160°
Absorption maximum: uv max (2-propanol): 220 nm (e 30000)
Derivative Type: Maleate
CAS Registry Number: 59467-94-6
Manufacturers' Codes: Ro-21-3981/001
Trademarks: Dormicum (Roche)
Molecular Formula: C18H13ClFN3.C4H4O4
Molecular Weight: 441.84
Percent Composition: C 59.80%, H 3.88%, Cl 8.02%, F 4.30%, N 9.51%, O 14.48%
Properties: Crystals from ethanol/ether, mp 114-117° (solvated). LD50 in male mice (mg/kg): 760 orally; 86 i.v. (Pieri).
Melting point: mp 114-117° (solvated)
Toxicity data: LD50 in male mice (mg/kg): 760 orally; 86 i.v. (Pieri)
Derivative Type: Hydrochloride
CAS Registry Number: 59467-96-8
Manufacturers' Codes: Ro-21-3981/003
Trademarks: Hypnovel (Roche); Versed (Roche)
Molecular Formula: C18H13ClFN3.HCl
Molecular Weight: 362.23
Percent Composition: C 59.68%, H 3.90%, Cl 19.57%, F 5.24%, N 11.60%
Properties: Sol in aqueous solns.